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Figure 10 | Veterinary Research

Figure 10

From: Trichinella spiralis galectin binding to toll-like receptor 4 induces intestinal inflammation and mediates larval invasion of gut mucosa

Figure 10

TAK-242 and PDTC inhibited rTsgal-activated transcription of NF-κB pathway and cytokines in Caco-2 cells. A, E qPCR analysis of rTsgal-activated expression of NF-κB p65 mRNA in Caco-2 cells treated with TAK-242 (A) and PDTC (E). B–D and F–H qPCR analysis of rTsgal-activated expression of IL-1β (B, F), IL-6 (C, G) and TGF-β (D, H) mRNA in Caco-2 cells treated with TAK-242 (B–D) and PDTC (F–H). *P < 0.0001 compared to the DMSO or PBS control group. #P < 0.05 compared to between the two groups.

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