Figure 11

TAK-242 and PDTC inhibited rTsgal-activated expression of NF-κB pathway proteins in Caco-2 cells. A, E Western blot analysis of rTsgal-activated expression of NF-κB p65 protein in Caco-2 cells treated with TAK-242 (A) and PDTC (E). B–D and F-H Western blot analysis of rTsgal-activated expression of p-ERK1/2 (B, F), p-NF-κB p65 (C, G) and NF-κB p65 (D, H) in Caco-2 cells treated with TAK-242 (B–D) and PDTC (F–H). *P < 0.0001 compared to the DMSO or PBS control. ^#P < 0.05 compared between the two groups.