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Figure 9 | Veterinary Research

Figure 9

From: Trichinella spiralis galectin binding to toll-like receptor 4 induces intestinal inflammation and mediates larval invasion of gut mucosa

Figure 9

TAK-242 and PDTC abrogated rTsgal-activated TLR-4 expression in Caco-2 cells. A, D qPCR analysis of rTsgal–activated TLR-4 mRNA expression in Caco-2 cells treated TAK-242 (A) and PDTC (D). B, E Western blot analysis of expression of rTsgal–activated TLR-4 protein expression in Caco-2 cells treated with TAK-242 (B) and PDTC (E). C, F comparison of rTsgal–activated TLR-4 protein expression in various groups of Caco-2 cells treated with TAK-242 (C) and PDTC (F). TAK-242 and PDTC distinctly abrogated the rTsgal-activated TLR-4 expression in Caco-2 cells. *P < 0.05 compared to the solvent (DMSO or PBS) group. #P < 0.05 compared to between the two groups.

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