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  1. Porcine epidemic diarrhoea (PED) caused by porcine epidemic diarrhoea virus (PEDV) has led to significant economic losses in the swine industry worldwide. Histone Cluster 2, H2BE (HIST2H2BE), the main protein ...

    Authors: Xingang Xu, Mingrui Ma, Xiaojie Shi, Yuchao Yan, Yi Liu, Naling Yang, Quanqiong Wang, Shuxia Zhang and Qi Zhang
    Citation: Veterinary Research 2023 54:27
    Content type: Research article Published on:

  2. Enterotoxigenic Escherichia coli (ETEC) colonizes the intestine of young pigs causing severe diarrhoea and consequently bringing high production costs. The rise of antibiotic selective pressure together with ongo...

    Authors: Alice Ferreira, Daniela Silva, Carina Almeida, Maria Elisa Rodrigues, Sónia Silva, Joana Castro, Dalila Mil-Homens, Isidro García-Meniño, Azucena Mora, Mariana Henriques and Ana Oliveira
    Citation: Veterinary Research 2023 54:26
    Content type: Research article Published on:

  3. Pseudorabies virus (PRV) causes viral encephalitis, a devastating disease with high mortality worldwide. Curcumin (CUR) can reduce inflammatory damage by altering the phenotype of microglia; however, whether a...

    Authors: Luqiu Feng, Guodong Luo, Yuhang Li, Chen Zhang, Yuxuan Liu, Yanqing Liu, Hongyue Chen, Daoling He, Yan Zhu and Ling Gan
    Citation: Veterinary Research 2023 54:25
    Content type: Research article Published on:

  4. Hepatitis-hydropericardium syndrome (HHS) induced by fowl adenovirus serotype-4 (FAdV-4) has caused large economic losses to the world poultry industry in recent years. HHS is characterized by pericardial effu...

    Authors: Ting Wang, Lizhen Wang, Wei Li, Xiaolan Hou, Wenchi Chang, Bo Wen, Shuizhong Han, Yan Chen, Xuefeng Qi and Jingyu Wang
    Citation: Veterinary Research 2023 54:24
    Content type: Research article Published on:

  5. Tembusu virus (TMUV) is an emerging flavivirus that has broken out in different regions of China. TMUV infection has been reported to induce autophagy in duck embryo fibroblast cells. However, the molecular me...

    Authors: Wangyang Tan, Senzhao Zhang, Yu He, Zhen Wu, Mingshu Wang, Renyong Jia, Dekang Zhu, Mafeng Liu, Xinxin Zhao, Qiao Yang, Ying Wu, Shaqiu Zhang, Juan Huang, Sai Mao, Xumin Ou, Qun Gao…
    Citation: Veterinary Research 2023 54:23
    Content type: Research article Published on:

  6. Orf virus (ORFV) is the causative agent of contagious ecthyma, which is an important zoonotic pathogen with a widespread distribution affecting sheep, goats and humans. Our previous research showed that autoph...

    Authors: Lijun Lv, Jiyu Guan, Ruixue Zhen, Pin Lv, Mengshi Xu, Xingyuan Liu, Shishi He, Ziyu Fang, Zi Li, Yungang Lan, Huijun Lu, Wenqi He, Feng Gao and Kui Zhao
    Citation: Veterinary Research 2023 54:22
    Content type: Research article Published on:

  7. The alphaherpesvirus pseudorabies virus (PRV) is the causative agent of pseudorabies, responsible for severe economic losses to the swine industry worldwide. The interferon-inducible GTPase guanylate-binding p...

    Authors: Xiaohua Zhang, Qian Du, Guiyuan Chen, Yiyuan Jiang, Kai Huang, Linghao Li, Dewen Tong and Yong Huang
    Citation: Veterinary Research 2023 54:21
    Content type: Research article Published on:

  8. Ovine brucellosis is a global zoonotic disease of sheep caused by Brucella melitensis, which inflicts a significant burden on human and animal health. Brucella suis strain S2 (B. suis S2) is a smooth live attenua...

    Authors: Si Chen, Yuanyuan Chen, Zizhuo Jiao, Chengqiang Wang, Dantong Zhao, Yongbin Liu, Wenguang Zhang, Shihua Zhao, Bin Yang, Qinan Zhao, Shaoyin Fu, Xiaolong He, Qiaoling Chen, Churiga Man, Guoying Liu, Xuefeng Wei…
    Citation: Veterinary Research 2023 54:20
    Content type: Research article Published on:

  9. Short-chain dehydrogenases/reductases (SDRs) regulate the activities of many hormones and other signaling molecules and participate in the deactivation of various carbonyl-bearing xenobiotics. Nevertheless, kn...

    Authors: Karolína Štěrbová, Nikola Rychlá, Petra Matoušková, Lenka Skálová and Lucie Raisová Stuchlíková
    Citation: Veterinary Research 2023 54:19
    Content type: Research article Published on:

  10. Vaccination is one of the most widely used strategies to protect horses against pathogens. However, available equine vaccines often have limitations, as they do not always provide effective, long-term protecti...

    Authors: Flora Carnet, Laure Perrin-Cocon, Romain Paillot, Vincent Lotteau, Stéphane Pronost and Pierre-Olivier Vidalain
    Citation: Veterinary Research 2023 54:18
    Content type: Review Published on:

  11. Streptococcus suis (S. suis) and Pasteurella multocida (P. multocida) are pathogens that can cause zoonotic diseases. P. multocida toxin (PMT) is an important virulence factor that causes atrophic rhinitis in pig...

    Authors: Min-Chia Wu, Hsing-Chieh Wu, Jai-Wei Lee, Wan-Chen Chang and Chun-Yen Chu
    Citation: Veterinary Research 2023 54:17
    Content type: Research article Published on:

  12. Mycoplasma hyopneumoniae is the primary agent of enzootic pneumonia in pigs. To minimize the economic losses caused by this disease, M. hyopneumoniae vaccination is commonly practiced. However, the persistence o...

    Authors: Evelien Biebaut, Lisa Beuckelaere, Filip Boyen, Freddy Haesebrouck, Charles-Oliver Gomez-Duran, Bert Devriendt and Dominiek Maes
    Citation: Veterinary Research 2023 54:16
    Content type: Research article Published on:

  13. Attenuated Salmonella Typhimurium is a promising antigen delivery system for live vaccines such as polysaccharides. The length of polysaccharides is a well-known key factor in modulating the immune response induc...

    Authors: Yue Han, Ping Luo, Huan Zeng, Pu Wang, Jiali Xu, Pengju Chen, Xindan Chen, Yuji Chen, Qiyu Cao, Ruidong Zhai, Jing Xia, Simin Deng, Anchun Cheng, Changyong Cheng and Houhui Song
    Citation: Veterinary Research 2023 54:15
    Content type: Research article Published on:

  14. Antimicrobial resistance is a global threat to human, animal, and environmental health. In pig production, antimicrobials and heavy metals such as zinc oxide are commonly used for treatment and prevention of d...

    Authors: Daniel Ekhlas, Héctor Argüello, Finola C. Leonard, Edgar G. Manzanilla and Catherine M. Burgess
    Citation: Veterinary Research 2023 54:14
    Content type: Review Published on:

  15. Bacterial chondronecrosis with osteomyelitis (BCO) is a common cause of broiler lameness. Bacteria that are found in BCO lesions are intestinal bacteria that are proposed to have translocated through the intes...

    Authors: Yue Huang, Venessa Eeckhaut, Evy Goossens, Geertrui Rasschaert, Johan Van Erum, Geert Roovers, Richard Ducatelle, Gunther Antonissen and Filip Van Immerseel
    Citation: Veterinary Research 2023 54:13
    Content type: Research article Published on:

  16. Enteroids are miniature self-organising three-dimensional (3D) tissue cultures which replicate much of the complexity of the intestinal epithelium. We recently developed an apical-out leukocyte-containing chic...

    Authors: Tessa J. Nash, Katrina M. Morris, Neil A. Mabbott and Lonneke Vervelde
    Citation: Veterinary Research 2023 54:12
    Content type: Research article Published on:

  17. Antimicrobial resistance (AMR) is a global health issue and surveillance of AMR can be useful for understanding AMR trends and planning intervention strategies. Salmonella, widely distributed in food-producing an...

    Authors: Chia-Chi Wang, Yu-Ting Hung, Che-Yu Chou, Shih-Ling Hsuan, Zeng-Weng Chen, Pei-Yu Chang, Tong-Rong Jan and Chun-Wei Tung
    Citation: Veterinary Research 2023 54:11
    Content type: Research article Published on:

  18. Avian pathogenic Escherichia coli (APEC) is the cause of colibacillosis outbreaks in young poultry chicks, resulting in acute to peracute death. The high morbidity and mortality caused by colibacillosis results i...

    Authors: Inger Helene Kravik, Håkon Kaspersen, Siri Kulberg Sjurseth, Katharine Rose Dean, Bruce David, Marina Aspholm and Camilla Sekse
    Citation: Veterinary Research 2023 54:10
    Content type: Research article Published on:

  19. Of the three branches of unfolded protein response (UPR) that were reportedly activated by porcine epidemic diarrhea virus (PEDV), PERK is recently shown to act as an upstream regulator of oxidative response o...

    Authors: Yingshan Zhou, Yuxin Zhang, Wanyu Dong, Shiqi Gan, Jing Du, Xingdong Zhou, Weihuan Fang, Xiaodu Wang and Houhui Song
    Citation: Veterinary Research 2023 54:9
    Content type: Research article Published on:

  20. Porcine respiratory disease is one of the most important health problems in pig production worldwide. Cranioventral pulmonary consolidation (CVPC) and pleurisy are the two most common lesions in the respirator...

    Authors: Dominiek Maes, Marina Sibila, Maria Pieters, Freddy Haesebrouck, Joaquim Segalés and Luís Guilherme de Oliveira
    Citation: Veterinary Research 2023 54:8
    Content type: Review Published on:

  21. Streptococcus suis serotype 2 (SS2) frequently colonizes the swine upper respiratory tract and can cause Streptococcal disease in swine with clinical manifestations of pneumonia, meningitis, and septicemia. Previ...

    Authors: Yu Meng, Shaojie Lin, Kai Niu, Zhe Ma, Huixing Lin and Hongjie Fan
    Citation: Veterinary Research 2023 54:7
    Content type: Research article Published on:

  22. The type VI secretion system (T6SS) is a secretion apparatus widely found in pathogenic Gram-negative bacteria and is important for competition among various bacteria and host cell pathogenesis. Hcp is a core ...

    Authors: Zhe Chen, Zhao Qi, Ziqi Li, Zichao Song, Xiaoru Wang, Ying Shao, Jian Tu and Xiangjun Song
    Citation: Veterinary Research 2023 54:6
    Content type: Research article Published on:

  23. Duck hepatitis A virus type 1 (DHAV-1) is an acute, highly lethal infectious agent that infects ducklings and causes up to 95% mortality in ducklings up to 1 week of age, posing a significant economic threat t...

    Authors: Xiaoyan Xia, Anchun Cheng, Mingshu Wang, Xumin Ou, Di Sun, Shaqiu Zhang, Sai Mao, Qiao Yang, Bin Tian, Ying Wu, Juan Huang, Qun Gao, Renyong Jia, Shun Chen, Mafeng Liu, Xin-Xin Zhao…
    Citation: Veterinary Research 2023 54:5
    Content type: Research article Published on:

  25. Fish health personnel have limited tools in combatting viral diseases such as heart and skeletal muscle inflammation (HSMI) in open net-pen farmed Atlantic salmon. In this study, we aimed to predict HSMI by in...

    Authors: Johan Rennemo, Steinar Myrvold, Kjetil Berge, Øyvind Kileng, Børge Pedersen, Dan Sindre Aksberg, Piotr Lisik, Delphine Crappe, Charles McGurk, Espen Rimstad, Øystein Wessel, Erling Olaf Koppang and Håvard Bjørgen
    Citation: Veterinary Research 2023 54:3
    Content type: Research article Published on:

  26. The expression of proinflammatory (IL-1β, IFN-γ, TNF-α) and regulatory (IL-10, TGF-β, IL-4) cytokines, as well as the transcription factor FoxP3, was quantified in the liver and hepatic lymph node (HLN) of she...

    Authors: María Teresa Ruiz-Campillo, Diana María Barrero-Torres, Nieves Abril, José Pérez, Rafael Zafra, Leandro Buffoni, Álvaro Martínez-Moreno, Francisco Javier Martínez-Moreno and Verónica Molina-Hernández
    Citation: Veterinary Research 2023 54:2
    Content type: Research Article Published on:

  27. Streptococcus suis serotype 2 is an important bacterial pathogen of swine, responsible for substantial economic losses to the swine industry worldwide. The knowledge on the pathogenesis of the infection caused by...

    Authors: Servane Payen, Jesús Aranda Rrodriguez, Mariela Segura and Marcelo Gottschalk
    Citation: Veterinary Research 2023 54:1
    Content type: Research Article Published on:

  28. Listeriolysin O (LLO) is the main virulence protein of Listeria monocytogenes (LM), that helps LM escape lysosomes. We previously found that the cellular immune response elicited by L.ivanovii (LI) is weaker than...

    Authors: Ruidan Li, Qian Liang, Sicheng Tian, Yunwen Zhang, Sijing Liu, Qian Ou, Zhaobin Chen and Chuan Wang
    Citation: Veterinary Research 2022 53:113
    Content type: Research article Published on:

  30. Chronic wasting disease (CWD) is a prion disease of cervids including deer, elk, reindeer, and moose. Human consumption of cervids is common, therefore assessing the risk potential of CWD transmission to human...

    Authors: Brent Race, Chase Baune, Katie Williams, James F. Striebel, Andrew G. Hughson and Bruce Chesebro
    Citation: Veterinary Research 2022 53:111
    Content type: Research Article Published on:

  31. Enterococcus cecorum (EC) is one of the most relevant bacterial pathogens in modern broiler chicken production from an economic and animal welfare perspective. Although EC pathogenesis is generally well described...

    Authors: Jana Schreier, Ivan Rychlik, Daniela Karasova, Magdalena Crhanova, Gerhard Breves, Silke Rautenschlein and Arne Jung
    Citation: Veterinary Research 2022 53:110
    Content type: Research Article Published on:

  32. The bursa of Fabricius, the acknowledged humoral immune organ unique to birds, plays a vital role in B cell development. Bursopentin (BP5) derived from the bursa is reported to induce the development and forma...

    Authors: Ze Zhang, Jiaxi Cai, Shanshan Hao, Chenfei Li, Jiajing Chen, Tongtong Li and Xiuli Feng
    Citation: Veterinary Research 2022 53:109
    Content type: Research Article Published on:

  33. To improve understanding of the pathobiology of highly pathogenic avian influenza virus (HPAIV) infections in wild birds, pathogenicity and transmissibility of HPAIV H5N8 subtype clade 2.3.4.4b was evaluated i...

    Authors: Karolina Tarasiuk, Anna Kycko, Małgorzata Knitter, Edyta Świętoń, Krzysztof Wyrostek, Katarzyna Domańska-Blicharz, Łukasz Bocian, Włodzimierz Meissner and Krzysztof Śmietanka
    Citation: Veterinary Research 2022 53:108
    Content type: Research Article Published on:

  34. Bovine respiratory syncytial virus (BRSV) is a major cause of respiratory disease in cattle. Genomic sequencing can resolve phylogenetic relationships between virus populations, which can be used to infer tran...

    Authors: Paul C. D. Johnson, Sara Hägglund, Katarina Näslund, Gilles Meyer, Geraldine Taylor, Richard J. Orton, Siamak Zohari, Daniel T. Haydon and Jean François Valarcher
    Citation: Veterinary Research 2022 53:107
    Content type: Research Article Published on:

  35. The “Zero by 30” strategic plan aims to eliminate human deaths from dog-mediated rabies by 2030 and domestic dog vaccination is a vital component of this strategic plan. In areas where domestic dog vaccination...

    Authors: Sarah Hayes, Kennedy Lushasi, Maganga Sambo, Joel Changalucha, Elaine A. Ferguson, Lwitiko Sikana, Katie Hampson, Pierre Nouvellet and Christl A. Donnelly
    Citation: Veterinary Research 2022 53:106
    Content type: Research Article Published on:

  36. Erysipelas, caused by infection with Erysipelothrix rhusiopathiae (ER) is an important emerging disease in laying hens. We have earlier observed prominent mannose-binding lectin (MBL) acute phase responses in exp...

    Authors: Eva Wattrang, Tina Sørensen Dalgaard, Rikke Brødsgaard Kjaerup, Mohammad Naghizadeh, Susanne Kabell, Helena Eriksson and Robert Söderlund
    Citation: Veterinary Research 2022 53:105
    Content type: Research article Published on:

  37. The protective arm of the renin-angiotensin system (RAS), the ACE 2/Ang-(1–7)/MasR axis, has become a new anti-inflammatory target. As a specific activator of ACE2, diminazene aceturate (DA) can promote anti-i...

    Authors: Xiangjun Zhang, Fang Jia, Weiwu Ma, Xueqiang Li and Xuezhang Zhou
    Citation: Veterinary Research 2022 53:104
    Content type: Research Article Published on:

  38. A disruption in the expression of gga-miR-365-3p was confirmed in the Mycoplasma gallisepticum (MG)-infected Chicken primary alveolar type II epithelial (CP-II) cells based on previous sequencing results, but the...

    Authors: Yingjie Wang, Yun Han, Lulu Wang, Mengyun Zou, Yingfei Sun, Huanling Sun, Qiao Guo and Xiuli Peng
    Citation: Veterinary Research 2022 53:103
    Content type: Research article Published on:

  39. Considering human decision-making is essential for understanding the mechanisms underlying the propagation of real-life diseases. We present an extension of a model for pathogen spread that considers farmers’ ...

    Authors: Lina Cristancho-Fajardo, Elisabeta Vergu, Gaël Beaunée, Sandie Arnoux and Pauline Ezanno
    Citation: Veterinary Research 2022 53:102
    Content type: Research article Published on:

  40. African swine fever virus (ASFV) is a large DNA virus that infects domestic pigs with high morbidity and mortality rates. Repeat sequences, which are DNA sequence elements that are repeated more than twice in ...

    Authors: Zhaozhong Zhu, Shengqiang Ge, Zena Cai, Yifan Wu, Congyu Lu, Zheng Zhang, Ping Fu, Longfei Mao, Xiaodong Wu and Yousong Peng
    Citation: Veterinary Research 2022 53:101
    Content type: Research article Published on:

  41. This research aimed to analyze the regulatory effect of chicken telomerase reverse transcriptase (chTERT) on the Wnt/β-catenin signaling pathway and its effect on the tumorigenicity of avian leukosis virus sub...

    Authors: Yong Xiang, Canxin Liang, Qingbo Li, Qinxi Chen, Yang Zhou, Xiaoxue Zheng, Di Zhou, Zepeng Wang, Guyao Wang and Weisheng Cao
    Citation: Veterinary Research 2022 53:100
    Content type: Research article Published on:

  43. Dairy cows often develop different degrees of endometritis after calving and this is attributed to pathogenic bacterial infections such as by Escherichia coli and Staphylococcus aureus. Infection of the bovine en...

    Authors: Jindi Wu, Fan Bai, Wei Mao, Bo Liu, Xiaolin Yang, Jing Zhang, Tingting Li, Gerelt Borjigin and Jinshan Cao
    Citation: Veterinary Research 2022 53:98
    Content type: Research article Published on:

  44. Klebsiella pneumoniae is a leading cause of severe infections in humans and animals, and the emergence of multidrug-resistant strains highlights the need to develop effective vaccines for preventing such infecti...

    Authors: Fusheng Zhang, Yan Meng, Li Xu, Yujiao Tian, Huigai Lu, Jichen Xie, Renhui Ma, Moran Li and Bei Li
    Citation: Veterinary Research 2022 53:97
    Content type: Research article Published on:

  45. Colistin is frequently used as a growth factor or treatment against infectious bacterial diseases in animals. The Veterinary Division of the European Medicines Agency (EMA) restricted colistin use as a second-...

    Authors: Afaf Hamame, Bernard Davoust, Bouthaina Hasnaoui, David Lupande Mwenebitu, Jean-Marc Rolain and Seydina M. Diene
    Citation: Veterinary Research 2022 53:96
    Content type: Research article Published on:

  46. Mycoplasma hyopneumoniae, the causative agent of swine respiratory disease, demonstrates differences in virulence. However, factors associated with this variation remain unknown. We herein evaluated the associati...

    Authors: Yuzi Wu, Yanfei Yu, Lizhong Hua, Yanna Wei, Yuan Gan, Hafizah Yousuf Chenia, Yixuan Wang, Xing Xie, Jia Wang, Maojun Liu, Guoqing Shao, Qiyan Xiong and Zhixin Feng
    Citation: Veterinary Research 2022 53:95
    Content type: Research article Published on:

  48. An alphaherpesvirus carries dozens of viral proteins in the envelope, tegument and capsid structure, and each protein plays an indispensable role in virus adsorption, invasion, uncoating and release. After inf...

    Authors: Tong Zhou, Mingshu Wang, Anchun Cheng, Qiao Yang, Bin Tian, Ying Wu, Renyong Jia, Shun Chen, Mafeng Liu, Xin-Xin Zhao, Xuming Ou, Sai Mao, Di Sun, Shaqiu Zhang, Dekang Zhu, Juan Huang…
    Citation: Veterinary Research 2022 53:93
    Content type: Review Published on:

  49. Multi-Locus Sequence Analysis (MLSA) of Mycoplasma capricolum subsp. capripneumoniae (Mccp) strains from Asia revealed unforeseen diversity and a central position for genotyping groups representing strains from C...

    Authors: Arooba Akhtar, Anne Boissière, Huafang Hao, Muhammad Saeed, Virginie Dupuy, Antoni Exbrayat, Farhan Anwar Khan, Yuefeng Chu and Lucía Manso-Silván
    Citation: Veterinary Research 2022 53:92
    Content type: Short report Published on:

  50. Foamy macrophages containing prominent cytoplasmic lipid droplets (LDs) are found in a variety of infectious diseases. However, their role in Streptococcus uberis-induced mastitis is unknown. Herein, we report th...

    Authors: Zhixin Wan, Shaodong Fu, Zhenglei Wang, Yuanyuan Xu, Yuanyuan Zhou, Xinguang Lin, Riguo Lan, Xiangan Han, Zhenhua Luo and Jinfeng Miao
    Citation: Veterinary Research 2022 53:90
    Content type: Research article Published on:
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